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OUTCOME OF KIDNEY TRANSPLANTS FROM LIVING DONORS IN PATIENTS WITH DSA

机译:DSA患者患者的肾脏移植的结果

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Anti-HLA DSA has been previously considered an absolute contraindication to transplantation. However, progress in antibody detection, desensitization, early diagnosis and treatment of antibody-mediated rejection (AMR) currently permits successful transplantation of sensitized recipients with kidneys from living donors. The objective of this study was to analyze the prognostic value of Complement Dependent Cytotoxicity (CDC), Flow Cytomery Cross Match (FCXM) and Solid Phase Assay (SPA) when used alone or together for pre-transplant evaluation of DSA.
机译:抗HLA DSA以前被认为是对移植的绝对禁忌症。然而,抗体检测,脱敏,早期诊断和治疗抗体介导的排斥(AMR)的进展目前允许成功将敏化受体移植与活捐赠者的肾脏移植。本研究的目的是分析单独使用或一起用于预移植DSA的预移植评估时,分析补体依赖性细胞毒性(CDC),流动细胞杂交交叉匹配(FCXM)和固相测定(SPA)的预后值。

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