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Rabies Control and Prevention in Georgia: Current Status and Perspectives

机译:格鲁吉亚狂犬病控制和预防:当前状态和观点

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The incidence of rabies post-exposure prophylaxis (PEP) is very high in Georgia; at 876/100,000 persons in 2006. Data from the National Centre for Disease Control on rabies surveillance for 200; 2005 and 2006 was analysed, with the objective of improving post-exposure policy and practice, as well as identifying priorities for national surveillance and control. For the base period 1986-199; a total of 40 rabies cases in humans were reported in Georgia. In 200; 2005 and 2006 there were 1;10 and 7 reported cases, respectively, representing a significant increase in overall incidence for this period. Ninety-three percent (93%) of cases were caused by dog bites. The large population of stray dogs and unvaccinated pets in Georgia is recognized as the mainrisk factor. In 200; 38,569 patients received PEP following bites by an animal with suspected rabies, compared to 2;712 in 200; and 30,254 in 2005 (representing a 1 /3 increase annually). Of the total number of PEP treatments initiated in 200;1;568 (69.9%) were discontinued due to the fact that the biting animal remained healthy during the observation period; 2;106 (76.4%) were discontinued in 2005; and 30,254 (78.4%) were discontinued in 2006. Concerns regarding the safety of available immunoglobulins, uncertainty regarding the use of vaccines and immunoglobulins from different manufacturers, and the inconsistency of national guidelines with international recommendations are cited as obstacles to an improved delivery of PEP. For the effective controlof rabies, the national veterinary programmes need to be improved, stray dog population control measures need to be updated according to international standards, and clear national guidelines regarding the use of rabies vaccines and immunoglobulins forPEP should be developed and implemented.
机译:狂犬病暴露的预防(PEP)的发病率在格鲁吉亚非常高; 2006年的876 / 100,000人。来自国家疾病控制中心的数据狂犬病监督2006年的数据;分析了2005年和2006年,目的是改善暴露后政策和实践,以及确定国家监测和控制的优先事项。 1986-199的基地期间;在格鲁吉亚报道了人类中共有40例狂犬病病例。 200; 2005年和2006年,分别有1; 10和7例报告案件,这一期间的总体发病率显着增加。猪咬伤引起了九十三(93%)的病例。格鲁吉亚的大量流浪犬和未接种疫苗的宠物被认为是主要因素。 200; 38,569名患者通过具有疑似狂犬病的动物接受叮咬的PEP,与2; 200年712;和2005年的30,254(每年代表1/3增加)。在200; 1; 1; 568(69.9%)中发起的PEP治疗总数是由于咬人在观察期间仍然健康而停止; 2; 106(76.4%)于2005年停产; 2006年停止了30,254(78.4%)。关于可用免疫球蛋白的安全性,有关使用来自不同制造商的疫苗和免疫球蛋白的不确定性的担忧,以及国家指南与国际建议的不一致被认为是改善PEP交付的障碍。对于狂犬病的有效控制,需要改进国家兽医计划,需要根据国际标准更新流浪犬人口控制措施,并明确有关使用狂犬病疫苗和免疫球蛋白的使用的明确国家准则和实施。

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