USE OF NEUPOGEN~R (FILGRASTIM) IN A BOTTLENOSE DOLPHIN (Tursiops truncatus)

摘要

In December 2006 all the dolphins from L'Oceanografic were removed from their exhibit and separated into several other minor enclosures during pool remodeling. When the work was finished 3 mo later, all the animals were placed back in the dolphinarium. During the previous week one young male dolphin (body weight was 126 kg) was already experiencing a social stress situation in his own small group. According to the unstable blood work, some relevant rake marks and the concern this animal was potentially immunocompromised, antibiotic treatment with amoxicillin + clavulanic acid (Augmentine~R, Glaxo Smith Kline, S.A. P.T.M. CI Severo Ochoa, 2. 28760 Tres Cantos, Madrid, Spain) at lOmg/kg PO BID was initiated and this animal was separated from the aggressive pool mate. Once in the dolphinarium, after 5 days of controlled regrouping of the entire original group, trauma from conspecifics resulted in new injuries, group isolation and eventually shock of this juvenile dolphin.