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Manufacturing of bone substitute implants using Selective Laser Melting

机译:使用选择性激光熔化制造骨代替植入物

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Selective Laser Melting (SLM) is a Rapid Manufacturing technique which enables direct manufacturing of three-dimensional parts with high bulk density on the base of individual three-dimensional data, including computer tomography models of anatomical structures. A new approach follows a regenerative strategy for manufacturing of bone substitute implants. The SLM process is adapted for bioresorbable materials (biopolymer, bioceramic) to build individual implants which will dissolve in the body and be replaced by new bone. The pore structure of the implant is essential for bony ingrowth especially for critical size defects. With the additive technique SLM it is possible to manufacture implants with a defined internal porous structure. Depending on the field of application different materials will gain different specifications concerning for example the degradation time in the body or the mechanical properties of the implant. Using Selective Laser Melting the manufacturing of individual bioresorbable implants will be possible. This work describes the new approach for the qualification of SLM to process polylactide (PLLA) and a composite material polylactide and β-tricalcium phosphate (PLLA/β-TCP). To achieve this the materials morphology has to be prepared for the SLM process and a processing window for the above mentioned materials has to be identified varying the process parameters such as laser power, scanning velocity and laser beam diameter. The process temperature is kept low to prevent degradation of the polymer during melting and to prevent a phase transition of the bioceramic β-TCP.
机译:选择性激光熔化(SLM)是一种快速制造技术,可以在各个三维数据的基础上直接制造具有高堆积密度的三维部件,包括解剖结构的计算机断层扫描模型。一种新方法遵循了制造骨替代植入物的再生策略。 SLM工艺适用于生物可吸收材料(生物聚合物,生物陶瓷),以构建将溶解在体内并被新骨代替的单独植入物。植入物的孔隙结构对于骨骼注入至关重要,特别是对于临界大小缺陷。利用添加技术SLM,可以用限定的内部多孔结构制造植入物。根据应用领域,不同的材料将获得有关例如身体中的劣化时间的不同规格或植入物的机械性能。使用选择性激光熔化,将可以制造各种生物可吸收植入物。这项工作描述了用于加工聚物(PLLA)和复合材料聚丙酯和β-磷酸钙(PLLA /β-TCP)的SLM鉴定的新方法。为了实现这一点,必须为SLM工艺制备材料形态,并且必须识别用于上述材料的处理窗口改变过程参数,例如激光功率,扫描速度和激光束直径。将过程温度保持低,以防止聚合物在熔化过程中降解,并防止生物蛋白β-TCP的相转变。

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