Dietary protein intakes and bone growth

摘要

Peak bone mass is a significant determinant of fracture risk later in life. Nutritional intakes, particularly proteins, are able to modulate the genetic potential, with effects starting as early as in utero. There is a positive correlation between yearly lumbar and femoral bone mass gain, and protein intake. Dairy products consumption positively influences bone mineral density at the spine, hip and forearm in adolescents, leading thereby to a higher peak bone mass. Nutritional intakes, particularly proteins, are associated to bone growth, hence to bone strength and resistance to fracture later in life. The growth hormone IGF-I-target organ axis is likely to be implicated in this process. Variations in the protein intake within the "normal" range can have a significant effect on skeletal growth and thereby modulate the genetic potential in peak bone mass attainment.