Monte Carlo simulation of the Optical Coherence Doppler Tomography signals from blood flows in light scattering media: problem of flow velocity profile reconstruction

摘要

Optical Coherence Tomography (OCT) and Optical Coherence Doppler Tomography (OCDT) signals from one and two plain flows of anon-aggregating paniculate suspension mimicking blood embedded into a stationary light scattering medium (2% Intralipid solution) with optical properties close to those of human skin were simulated implementing the Monte Carlo method. The role of multiple scattering in the OCT signals was analyzed. The maximal visualization depths for OCT imaging of different biotissue-like samples were estimated. It was shown that with an increase of embedding depth of the flow the reconstructed velocity values are smaller than the predefined ones and the reconstructed profile is stretched towards the rear border. In the case of two flows, it was shown that with an increase of the first flow velocity the reconstructed velocity values of the second flow increase too.