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Physico-chemical and biochemical approaches to assessing the development of precancerous pathologies of the gastrointestinal tract during their modeling in mice with complex effects of stress factors of different nature

机译:分布效应不同自然胁迫因素的小鼠胃肠道胃肠道癌前病变发展的生物化学方法

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It was shown in the experience with 60 white mice that separate and combined effects of stress factors - noctidial lighting (800 lux), sodium nitrite (0.2% solution in water) and p-toluidine (with food) within 107 days causes a change in impedance value of erythrocytes at frequencies 1Hz - 1MHz. Changes in the activity of intracellular aminotransferases, creatinine and urea were observed, indicating cardiotoxic and hepatotoxic effects.
机译:它以60个白老鼠的经验显示,将应力因素的分离和综合影响 - 愈合灯光(800勒克斯),亚硝酸钠(水中0.2%溶液)和对甲苯胺(用食物)在107天内导致变化导致变化红细胞的阻抗值1Hz - 1MHz频率。观察到细胞内氨基转移酶,肌酐和尿素的活性的变化,表明心脏毒害和肝毒性作用。

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