By using on-chip lenses and fluidic operations to control focal length and direction of a laser beam, two kind of new concepts are proposed. One is a device to generate and control micro bubbles inside a microfluidic chip. The generation and positional control of microbubbles are achieved by heat with a focused laser beam, which focal length is controlled by microfluidics. Second is a new optical paths control method by microfluidic operation. By changing the flow rates of two liquids having different refractive indices (R.Is), optical paths in the PDMS microfluidic chip is controlled. To demonstrate the functionality of the optical paths control, the present method was utilized for optical tweezers applications.
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