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Optofluidic Intracavity Spectroscopy for Single Cell Detection

机译:单细胞检测的Optof流体腔内光谱学

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Biological cells inside an optofluidic cavity modify the optical cavity modes, providing a probe for optical properties of the cells that can be used to detect and differentiate single cells. The fabrication and characterization of an optofluidic Fabry-Perot (FP) cavity in glass substrates for this purpose and initial results on obtaining single biological cell spectra were previously reported. Spectra of single biological cells including yeast cells and human blood cells using the optofluidic resonant cavity will be reported in this work. A method for spectral correlation is also presented to verify the preliminary results of the single cell spectra. The correlation calculation demonstrates that the method is able to differentiate some types of single cells.
机译:邻接物流体腔内的生物细胞改变光学腔模式,为可用于检测和分化单个细胞的电池的光学性质提供探针。玻璃基板中的晶体法布里 - 珀罗(FP)腔的制造和表征以此目的和初始导致获得单一生物细胞光谱的初始结果。在这项工作中,将报告包括使用邻晶谐振腔的酵母细胞和人血细胞的单一生物细胞的光谱。还提出了一种用于频谱相关的方法以验证单个小区谱的初步结果。相关性计算表明该方法能够区分某些类型的单细胞。

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