Fluorescence based sensors are used for determining environmental parameters such as dissolved oxygen or pH in biological systems. Such optical sensing techniques can provide real time monitoring capabilities without disturbing a biological system's equilibrium. Recently, there has been a drive to provide biological analysis tools in a compact form, usually resulting in arrays of miniature devices which can perform multiple functions or operations in parallel such as bacteria cultures, cell counting, or DNA analysis [1,2,3]. As these new types of chips become more integrated and parallel, the number of sensors required increases, which leads to an increase in the size and complexity of off-chip detection systems.
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