Effect of ZrO_2 on Mechanical and Biological Properties of Calcium Phosphate-Based Glass-Ceramics for Biomedical Applications

摘要

The effect of ZrO_2 addition on mechanical and biological properties of bioactive glass-ceramics with chemical compositions of 60CaO-30P_2O_5-3TiO_2-xZrO_2-(7-x)Na_2O (x=0,1,3) was investigated. It was found that ZrO_2 addition up to 3 mol% contributes to monotonical increase of the glass transition temperature. The micro-hardness increases slightly by 1 mol% ZrO_2 addition and keeps constant with further addition whereas 1 mol% ZrO_2 addition results in ～20% increase of three-point bending strength. When the specimens were soaked in simulated body fluid, complete apatite layers were formed on the specimens regardless of the ZrO_2 addition. It is therefore concluded that the toughening contribution of 1 mol% ZrO_2 addition has no adverse effect on the bioactivity of calcium phosphate glass-ceramics.