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A Level-2 Biosafety Beamline for Macromolecular Crystallography at SSRF

机译:SSRF的大分子晶体学级-2 Biosafety光束线

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A biosafety level-2 beamline for macromolecular crystallography is constructing at SSRF, which is one of the beamlines in phase-II beamline project approved at 2016 by the central government of China. This beamline will provide the capability of conducting the experiment on determination of the virus-related protein structure from crystals. To fulfill this aim, the end station is emphasized on the biosafety design which must meet the Chinese laws and regulations. For the limited source of insertion section in the storage ring, the beamline will be one of the canted beamline, sharing the insertion with the ultra-small angle X-ray scattering beamline. The photon source will be a 1.6 m long, in-vacuum undulator with period of 22 mm. The optics will consist of a deflection flat mirror to increase the distance of two canted beamline, a cryogenically cooled Si(111) doublecrystal monochromator and focusing mirrors. The focus scheme is realized with two-stage focus scheme in horizontal and one stage focus in vertical direction. At the sample position the focused beam is 20 micron in horizontal and 10 micron in vertical. The beam size could be changed by inserting the compound refractive lens. The beamline will deliver a high flux beam in the 7-18 keV energy range, with the energy resolution of AE/E~2×10~(-4). In addition to the main beamline, the endstation will be negative pressure control and be functional divided to meet the biosafety regulations. This report shows the current status of the beamline design.
机译:用于大分子晶体学的生物安全水平-2波束线是在SSRF的构建,这是2016年中央政府批准的II期束线项目中的波束线之一。该光束线将提供关于从晶体中测定病毒相关蛋白质结构的实验的能力。为了实现这一目标,在生物安全设计上强调了最终站,必须符合中国法律法规。对于存储环中的有限插入部分来源,光束线将是倾斜束线之一,与超小角X射线散射束线共享插入。光子源将是1.6米长的真空波浪,周期为22毫米。光学器件将包括偏转平面镜,以增加两个倾斜梁线的距离,冷冻冷却的Si(111)双夹单色单色器和聚焦镜。焦点方案用水平的两级焦点方案实现,垂直方向上的一级聚焦方案实现。在样品位置,聚焦光束在水平和10微米的垂直时为20微米。通过插入复合折射镜,可以改变光束尺寸。光束线将在7-18 kev能量范围内提供高通量光束,通过AE / E〜2×10〜(-4)的能量分辨率。除了主束线外,封面将是负压控制,并具有功能分为,以满足生物安全法规。此报告显示了BeamLine Design的当前状态。

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