1. SYNTHESIS OF LY455169-2H2, A MODEL STUDY FOR THE TRITIUM LABELING OF LY459477. 2. SYNTHESIS OF LY459477-3H2

摘要

LY459477 is a potent mGliiR agonist.1 Tritiated material was required for use in receptor binding assays. To support in vitro receptor binding studies, a tritium labeled isotopomer with a high specific activity (over 20 Ci/mmol) was required.