Continuous Enzymatic Reactive Distillation with Immobilized Enzyme Beads(PPT)

摘要

1. Feasibility of Enzymatic Reactive Distillation with enzyme beads was proven in pilot-scale 2. Reproducibility was demonstrated 3. Most promising operation variables 3.1 High distillate-to-feed-ratio (> 0.6 kg/kg) 3.2 High reflux ratio (> 5 kg/kg) 3.3 Reasonable high BuOH-feed (> 0.3 kg/h) 4. Outlook 4.1 Modeling/model validation 4.2 Influence of ultrasound on enzyme kinetics and stability 4.3 Investigate synthesis of chiral compounds in Enzymatic Reactive Distillation