AN ELECTROPHYSIOLOGICAL STUDY OF CHEMOTHERAPEUTIC AGENTS ON CANCEROUS CELLS USING DIELECTROPHORESIS (DEP)

摘要

Sin the first demonstration of the separation of live and dead yeast in 1966, dielectrophoresis (DEP) has been widely employed for examining the biophysical basis of the differnces between different cells. Electrophysiological properties such as the conductivity and permittivity of the membrane and cytoplasm of the cells can be obtained through using DEP through the fitting of a single-shell model to spectra correlating to the frequency-dependent change in the Clausius-Mossotti factor.