Influence of styryl dyes on blood erythrocytes

摘要

It was studied the influence of F, Sbt, Sil, Sbo monomer and homodimer Dst-5, Dst-10, Dbt-5, Dbt-10, Dil-10, Dbo-10 styryl dyes on blood erythrocytes of white rats. It was shown that the homodimer styryldyes Dst-5, Dbt-5 and Dbo-10 decrease the erythrocytes quantity by 1.5-2 times more as compared withmonomer dyes Sbt and Sbo. The main cause of dyes different action is the different oxidation degree ofintracellular hemoglobin evoked by these dyes. It was established that the observed effects was connectedwith different penetration of these dyes through membrane of erythrocytes and with interaction of these dyeswith albumin localized in membranes of cells.