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In Vivo Evaluation of a Guidance System for Computer Assisted Robotized Needle Insertion Devoted to Small Animals

机译:在体内评估计算机辅助机器化针插入的指导系统,专门用于小动物

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To improve therapy research against cancer, we propose a robotized computer assisted system for needle insertion devoted to the small animal. The system is composed of a robotic arm on which the needle is attached and two cameras rigidly linked. It needs a preoperative CT acquisition in which the biologist defines an entry point and the target he wants to reach. The needle guidance is ensured by a visual servoing and the needle is registered in the CT frame using radio-opaque markers stuck beforehand on the small animal. Biologists estimate that such a system can be beneficial if the time preparation per animal remains below 15 minutes and if the insertion accuracy is within 1 mm. Several error sources can be identified: the error due to the system only, the organ repositioning error (due to breathing motions) and the error induced by the needle insertion. In this paper, we report an evaluation on living rats of the system error and of the organ repositioning error. Encouraging results show that a global accuracy of 0.9 mm may be reached with an acceptable preparation time.
机译:为了改善癌症的治疗研究,我们提出了一种机器化计算机辅助系统,用于针对小动物的针插入。该系统由连接针附着的机器人臂组成,并且两个相机刚性连接。它需要术前CT采集,其中生物学家定义了他想要达到的入口点和目标。通过目视伺服装置确保针引导,并且使用预先在小动物上陷入困境的无线电透明标记物在CT帧中登记针。生物学家估计这种系统可以是有益的,如果每只动物的时间准备在15分钟以下,并且插入精度在1毫米内。可以识别几个误差源:仅由系统引起的错误,器官重新定位误差(由于呼吸动作)和针插入引起的错误。在本文中,我们报告了系统误差和器官重新定位误差的生活大鼠的评估。令人鼓舞的结果表明,可以通过可接受的准备时间达到0.9毫米的全球精度。

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