首页> 外文会议>PMSE Symposia >Development of Antimicrobial Peptides (AMPs) for Use in Self Decontaminating Surfaces
【24h】

Development of Antimicrobial Peptides (AMPs) for Use in Self Decontaminating Surfaces

机译:抗菌肽(AMPS)用于自净化表面的抗菌肽(AMPS)

获取原文

摘要

Antimicrobial peptides (AMPs) are a class of short polypeptides usually associated with the host organisms innate immune system . AMPs have been identified in a wide range of host organisms, including plants, amphibians, fish, and humans . AMPs usually consist of 30-100 amino acids, and are most often cationic. In addition to a net positive charge, AMPs often are amphipathic, containing both hydrophobic and hydrophilic domains. This property allows for increased interaction with and insertion into negatively charged cell walls and membranes of microbes . Several modes of action have been suggested for AMPs, and while the ‘carpet mechanism’ is the most supported theory, it is likely that AMPs act on microorganisms via a variety of routes .
机译:抗微生物肽(AMPS)是一种通常与宿主生物体生物体免疫系统相关的短多肽。 AMPS已在广泛的宿主生物中鉴定,包括植物,两栖动物,鱼和人类。安培通常由30-100氨基酸组成,最常阳离子。除了净阳性电荷之外,AMPS通常是两亲性,含有疏水性和亲水结构域。该特性允许增加与和插入带负电的细胞壁和微生物膜中的相互作用。已经为AMPS建议了几种行动模式,而“地毯机制”是最受支持的理论,AMPS很可能通过各种路线对微生物作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号