Effects of Fiber Alignment on the Behavior of Human Dermal Fibroblasts on the Three- Dimensional Poly (Methyl Methacrylate) (PMMA) Electrospun Scaffolds

摘要

Scaffolds of specific 3D geometry have been and will continue to be used in tissue engineering, since they have the ability to promote and control, via topographic stimuli, cell differentiation and tissue establishment, thereby increasing the quantity and range of material suitable for grafts [1-3]. Central to this strategy is achievement of a precisely patterned 3D scaffold to which mammalian cells can preferentially adhere.