FUNCTIONALIZATION OF C_(60) WITH DIPHOSPHONATE GROUPS: A ROUTE TO BONE-VECTORED FULLERENES

摘要

Since the discovery of a method in 1990 for the efficient production of macroscopic quantities of fullerenes,potential applications for these materials have been explored intensively.One of the most promising areas of this research now appears to be in the field of medicine.[1] The continued development of such applications will,in general,require functionalization of fullerenes with tissue-targeting moieties to help insure the delivery of any drug to a specific site in the body.