The central United States (U.S.) has a large livestock population including cattle, swine, sheep and goats that are susceptible to foot and mouth disease (FMD). Because FMD is a highly infective foreign animal disease, the only method to assess the impact of an introduction and effectiveness of control is through modeling. We developed simulation scenarios to assess the impact of an FMD introduction in the central U.S. and the effect of vaccination strategies and variation in biosecurity on FMD outbreaks using the North American Animal Disease Spread Model (NAADSM), a spatially explicit, stochastic infectious disease model.
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