Interferon Gamma Assay (Bovigam) for Bovine TB: Field Performance Analysis

摘要

This analysis addresses the field performance of the G-IFN in US herds between 2005 and 2009 and provides feedback on test behavior to those who apply the test and use test results to manage individual animals or herds. The specific objectives of theanalysis were (1) to estimate diagnostic sensitivity (SE) and specificity (SP) of the G-IFN under field conditions, (2) to assess the association between G-IFN test results, TB status of cattle and post mortem test results in animals slaughtered due to TB suspicion in the United States, and lastly (3) to explore the variability of the G-IFN optical densities and different cut-off points for classification of test results in adult cattle.