INTERACTION OF CELLULOSE WITH PROTEINS

摘要

Adsorption of human serum albumin (HSA) to mi-crocrystalline cellulose (MCC) interface has been determined as functions of protein concentration and pH of the aqueous medium. The maximum adsorption value is reached at the HSA isoelectric point The isotherms with respect to the adsorption of HSA are S-shaped in character. The study of adsorption at several values of pH of the medium indicates that interaction of HSA with the MCC interface is not controlled by the electrostatic effect. The desorption data reveal that HSA is strongly bound to the MCC matrix.