Noninvasive Imaging and Analysis of Biological Tissue Structure, Function and Abnormalities with Optical Coherence Tomography

摘要

Optical coherence tomography (OCT) is a novel noninvasive optical imaging technique that enables cross-sectional imaging of highly scattering biological tissues at the axial resolution of 10 micrometers or less. Technological advances in our laboratory and others have permitted high-contrast and high-resolution OCT imaging of turbid biological tissues at depths of up to 2-3 mm, highly desirable for screening various kinds of superficial lesions and the invasion of these lesions.