RESISTANCE MANAGEMENT RATIONALE AND STRATEGY FOR WIDESTRIKETM INSECT PROTECTION (CRY1F/CRY1AC) IN COTTON

摘要

A resistance management strategy for WideStrike Bt cotton has been developed based on the doses of the Cry1F and Cry1Ac Bt proteins against the key target pests, their mode of action, and the biology of the target pests. This paper describes the scientific basis of the IRM plan and the resistance management plan options available to growers of WideStrike Bt cotton. Computer simulation modeling was conducted to understand how the target pests may adapt to WideStrike in realistic agroecosystems where multiple crops are grown and multiple Bt traits are used. The model integrated our knowledge of insecticidal dose, cross-resistance potential, pest biology and likely use patterns. This modeling showed that the rate of adaptation is likely to be very slow. The use of standard refuge practices will provide additional assurance that WideStrike will remain durable for the long term.