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High-frequency ultrasound miniature transducers for tissue imaging

机译:用于组织成像的高频超声微型传感器

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We have fabricated a miniature 120-MHz transducer for imaging the internal structure of living samples, and mounted it in a 3-mm-diameter rod-shaped probe which ensures contact with a tissue to evaluate the tissue imaging capability of the transducer. The transducer consists of a thin film of 12.5-micrometer thick ZnO sandwiched between two metal electrodes, the bottom one deposited on a sapphire substrate whose other face has a polished concave-sphere acoustic lens. Both the lens diameter and the sphere radius are 0.5 mm; that is, the F number of the lens is 1. The lens of the transducer faces outwards in the probe so that the ultrasound can be transmitted and received directly by it in the radial direction of the rod without any mirrors. As the probe rotates mechanically around its axis and shifts in the direction of the axis, a cylindrical plane created by the locus of the beam focus is located inside of the tissue. Using this scanning, we form tissue images in the C-scan mode in a cylindrical plane within the target tissue. Preliminary results for imaging an in vitro bovine kidney sample into which the probe was inserted demonstrate that the fabricated probe can image microscopic structure inside tissue samples.
机译:我们已经制造了一种微型120-MHz换能器,用于成像活样品的内部结构,并将其安装在3毫升直径的杆状探针中,其确保与组织接触以评估换能器的组织成像能力。换能器由薄膜组成12.5微米厚的ZnO夹在两个金属电极之间,底部沉积在其它面具有抛光的凹面声学透镜上的蓝宝石衬底上。透镜直径和球半径都为0.5毫米;也就是说,镜头的F数是1.换能器的透镜在探针中向外面向,使得可以在杆的径向方向上直接传递和接收,而无需任何镜子。当探针围绕其轴线机械地旋转并在轴线的方向上换档时,由光束焦点的轨迹产生的圆柱形平面位于组织的内部。使用该扫描,我们在目标组织内的圆柱形平面中形成C扫描模式中的组织图像。插入探针的体外牛肾脏样品的初步结果表明,制造的探针可以在组织样品内部图像微观结构。

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