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High-frequency ultrasound miniature transducers for tissue imaging

机译:高频超声微型换能器,用于组织成像

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Abstract: We have fabricated a miniature 120-MHz transducer for imaging the internal structure of living samples, and mounted it in a 3-mm-diameter rod-shaped probe which ensures contact with a tissue to evaluate the tissue imaging capability of the transducer. The transducer consists of a thin film of 12.5-micrometer thick ZnO sandwiched between two metal electrodes, the bottom one deposited on a sapphire substrate whose other face has a polished concave-sphere acoustic lens. Both the lens diameter and the sphere radius are 0.5 mm; that is, the F number of the lens is 1. The lens of the transducer faces outwards in the probe so that the ultrasound can be transmitted and received directly by it in the radial direction of the rod without any mirrors. As the probe rotates mechanically around its axis and shifts in the direction of the axis, a cylindrical plane created by the locus of the beam focus is located inside of the tissue. Using this scanning, we form tissue images in the C-scan mode in a cylindrical plane within the target tissue. Preliminary results for imaging an in vitro bovine kidney sample into which the probe was inserted demonstrate that the fabricated probe can image microscopic structure inside tissue samples. !13
机译:摘要:我们制造了一个用于对活体样品的内部结构进行成像的微型120 MHz传感器,并将其安装在直径3毫米的杆状探针中,该探针可确保与组织接触以评估该传感器的组织成像能力。该换能器由一个夹在两个金属电极之间的12.5微米厚的ZnO薄膜组成,最下面的一层沉积在一个蓝宝石衬底上,该衬底的另一面具有抛光的凹球声透镜。透镜直径和球面半径均为0.5 mm;也就是说,透镜的F数为1。换能器的透镜在探头中朝外,因此超声波可以直接在棒的径向上发射和接收超声波,而没有任何反射镜。当探针围绕其轴线机械旋转并沿轴线方向移动时,由束焦点的轨迹创建的圆柱平面位于组织内部。使用此扫描,我们在目标组织内的圆柱平面中以C扫描模式形成组织图像。对插入了探针的体外牛肾样品进行成像的初步结果表明,所制造的探针可以对组织样品内部的微观结构进行成像。 !13

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