Architecture of Nanostructured InclusionComplexes Composed of Amylose andSynthetic Polymers in PolymerizationSystems

摘要

Biological macromolecules such as proteins, nucleic acids, andpolysaccharides are vital materials for important in vivo functionsassociated with "living." The important biological functions of thesemacromolecules appear to be controlled not only by their primarystructures but also by higher-ordered structures, for example, by thedouble helix of DNA. Therefore, the research field covering theprecision architecture of synthetic macromolecules with higherstructural orders, so-called "supramolecular chemistry," has recentlygrown in importance from the perspective of corroborating biologicalstudies.' The higher-ordered structures of the biologicalmacromolecules such as DNA are simultaneously controlled as theyform in living systems. Therefore, control of higher-ordered structuresof synthetic polymeric supramolecules in the polymerization systemhas became new and important research topic from the viewpoint ofbioinspired concept, which will result in construction of new polymericmaterials. Based on this concept, we have recently found a newmethodology for forming nanostructured supramolecules composed ofamylose and synthetic polymers, which was achieved by means ofamylose-forming polymerization.2'3 In this presentation, we report theresults of our investigations of this methodology.