Chiral 1,3-Octanediol Synthetic Studies Using Enzymatic Methods as Key Steps

摘要

Synthesis of both enantiomers of 1,3-octanediol was accomplished via chiral 1-octen-3-ol. Enzymatic optical resolution was adopted as the key step for obtaining chiral 1-octen-3-ol. Both enantiomers of 1,3-octanediol were transformed into their glucosides enzymatically. The acetals of the diol were also synthesized. Enzymatic reaction played a major role in the synthesis of chiral 1,3-octanediol and its derivatives. Sensory evaluation was performed on all of the samples.