Photophysics of sulphonated aluminum phthalocyanines in reversed micelles

摘要

The photophysics of sulphonated aluminum phthalocyanines, AlPcS$-n$/ (n $EQ 0, 1, 2, 3 or 4), potential second-generation phototherapeutic agents for tumors, in cationic reversed micelles of benzyl ammonium hexadecyl chloride (BHDC) and anionic reversed micelles of sodium di(2-ethylhexyl) sulphosuccinate (AOT) have been investigated. Absorption spectroscopy, as well as steady state and time-resolved fluorescence emission studies, indicate that in BHDC the di- and tri-sulphonated derivatives are essentially monomeric whereas in AOT only the di-sulphonated phthalocyanine was found to be monomeric. The distribution of AlPcS$-n$/ in the reversed micelles, which appears to be strongly influenced by the extent of sulphonation and the environment of the reversed micelle, is discussed. It is anticipated that extrapolation can then be made to heterogeneous systems such as are found in biomembranes.