Implantation of Elongated Silicon Neural Probe Array in Rat Cortex

摘要

Neural microprobes represent an important component of neural prosthetic systems where implanted microprobes record the electro-potentials generated by specific thoughts in the brain and convey the signals to algorithms trained to interpret these thoughts. Here, we present novel elongated multi-site neural probe that can reach depths greater than 10mm. We hypothesize that reaching such depth allows the recording of cognitive signals required to drive cognitive prosthetics. The impedance of the recording sites on the probes was in the order of 500 kΩ at 1 kHz, which is consistent with probes used for neurophysiological recordings. We implanted the elongated probe in rats and showed that the elongated probes are capable of recording spikes from various recording sites.