The effect of Cutaneous Candidiasis infection on some physiological and immunological parameters

摘要

This study included the collection of 50 skin peel samples and withdrawal of blood samples from patients who infected with Cutaneous Candidiasis, 18 samples of yeast were isolated, including Candida albicans which represented 50% of the total number of positive samples, Candida spp 39% and Tricho lnkin 5.5% and Kloeckera spp by 5.5%. The study included the measuring the changes in the levels of some physiological and immunological parameters in the blood samples of patients who infected with Cutaneous Candidiasis and comparing with the control group. The results showed a significant decrease in the total number of white blood cells, a significant decrease in lymphocytes, a significant increase in Granocytes and elevation were insignificant in the monocytes of patients with Cutaneous Candidiasis compared to control group. The results of the study also showed a significant decrease in the values of superoxide dismutase (SOD) and catalase (CAT), as well as a significant decrease in the value of IgE of patients with candidiasis compared to control group. In addition, there was a significant increase in the value of IgA of patients with Cutaneous Candidiasis compared to the control group.