ApoH as a tool for ultrasensitive detection of pernicious microorganisms and to extract metagenomic data in low concentration pathogens

摘要

The ApoHα pre-analytical step is simple, fast, of broad usage, and compatible with multiplexing detection of viruses & bacteria: 1. by enhancing the sensitivity of existing viruses detection ApoHa provides major competitive advantages for: (1) early diagnosis of infection and diseases leading to better individual prompt treatment strategy, (2) Fine tuning of therapeutic monitoring consequently with an improved adaptation of therapeutic protocols. (3) earlier patient isolation as needed. 2. by improving: (1) epidemiological surveillance, (2) reduction of infectious disease risks during transfusions & transplantations. These factors are particularly useful in case of life-threatening infections (septicemia..) or, of HAI screening. 3. For bacterial contamination, ApoH allows their capture for ultra-sensitive detection significantly reducing the time to the results of the existing culture and PCR techniques.