Characterization of sunscreen cream containing benzophenone-3,3',4,4'-tetracarboxylate dianhydride

摘要

The purpose of this research was to evaluate in-vitro sunscreen activity of a cream formulation containing benzophenone-3,3',4,4'-tetracarboxylate dianhydride(BTDA).Sunscreen is used to protect skin from the adverse effects of ultraviolet(UV)A(320-400 nm)and UVB(290-320 nm)radiation.The most common chemical sunscreen is derivatives of benzophenone.The potency of benzophenone-3,3',4,4'-tetracarboxylate dianhydride for sun protection was evaluated using in-vitro spectrophotometric technique.Several cream formulation containing 5%(Fl),6%(F2),and 7%(F3)BTDA were designed.These cream were subjected to physical characteristic such as,organoleptic,viscosity,homogeneity,pH,spreadability,adhesivity,and stability(tuliskan satuan-bila ada).The sun protection factors(SPF)were analyzed by spectrophotometry using samples irradiated with UV in B region.All cream formulations showed good physical characteristics.The formulation of sunscreen cream containing BTDA meets the requirements of physical properties.SPF values of BTDA,Fl,F2,and F3 were 6.40±0.21;0.27±0.03;0.87±0.01;and 0.56±0.00,respectively.All cream formulations of sunscreen cream containing BTDA meets the requirements of physical properties with satisfactory characteristics,but does not indicate any sun protection activities.