The Effect of Freeze-Thaw Treatment to the Properties of Gelatin- Carbonated Hydroxy Apatite Membrane for Nerve Regeneration Scaffold

摘要

One of the major challenges in the development of scaffold for nerve regeneration is enhancing mechanical strength of the material to avoid the scaffold to rapidly degrade during regeneration process in nerve system. The aim of this study was to reveal the effect of freeze-thaw to the properties of gelatin-carbonated hydroxy apatite (CHA) membrane in two ratios 7 to 3 and 6 to 4 for gelatin to CHA respectively. Some variations of freeze-thaw cycles were applied for both ratios, which is referred for its biocompatibility in cells.