Unique Dicarboxylate Ion Incorporation in Octacalcium Phosphate

摘要

Various dicarboxylate ions can be incorporated into the crystal structure of octacalcium phosphate (OCP). This unique property can be applied to develop functional bone substitute materials. However, there are many unclear points regarding the chemistry of OCP with incorporated dicarboxylate ions. In this review, we discuss the following three topics regarding the fundamental properties of OCP with incorporated dicarboxylate ions: the incorporation of two types of dicarboxylate ions into the OCP interlayer, the precise control of the interplanar spacing for OCP with dicarboxylate ions having a side chain, and the chirality recognition of guest molecules during OCP incorporation phenomena.