PREPARATION METHOD OF BRUSHITE AND OCTACALCIUM PHOSPHATE GRANULES

摘要

Brushite (DCPD, dicalcium phosphate dihydrate, CaHPO₄-2H₂O) and octacalcium phosphate (OCP, Ca₈(HPO₄)₂(PO₄)₄-5H₂O) granules in the millimetre size range were prepared by using using calcium carbonate granules of marble-origin as the starting material. The method of the invention comprised of soaking the marble granules in aqueous solutions containing phosphate and/or calcium ions at temperatures between 20° and 75°C. The load-bearing DCPD and OCP granules of this invention are useful in maxillofacial and orthopedic void/bone defect filling and grafting applications.