Design and development of two channel portable Near Infrared Spectroscopy system for studies of cerebral oxygenation in prefrontal cortex of human brain

摘要

Functional near infrared spectroscopy is a noninvasive, non harmful, low cost and safe optical technique that can be used to study the functional activities in the human brain. This paper describes the development of two channel Near InfraRed Spectroscopy(NIRS) system and the results of the cerebral oxygenation changes during the different cognitive tasks. The objective of the study is to design, develop a portable non-invasive continuous wave NIRS system with dual wave length for determining the hemoglobin content of the blood chromophores during different activities of the prefrontal cortex of the brain. The two channel NIRS system designed and it was tested with 20 healthy, ie., 15 males and 5 females with an average age group of 21±2.25, they were given a 2 different mental tasks such as sequential subtraction (mathematical task) and spot the difference (Visuo-spatial task) and their Oxy & de-Oxy hemoglobin concentration was measured which showed more changes during the task period when compared to relaxation in both left and right part of pre-frontal cortex.