Synthesis and Structural Study of 4-(2-Chlorophenyl)-2-Ethoxy-5,6,7,8,9,10-HexahydrocyclooctaBPyridine-3-Carbonitrile

摘要

The novel organic material C_(20)H_(21)ClN_2O was synthesized by One-Pot synthesis method and the single crystals were grown by slow evaporation solution growth technique. The crystal structure was elucidated by subjecting the grown crystals to the single crystal x-ray diffraction analysis and was refined by full matrix least-squares method to R=0.039 for 2746 reflections. Crystal system of the grown crystal was found to be monoclinic with the space group P2_1/a and a=9.196(4) A, b=13.449(4) A, c=14.818(4) A, β= 101.542(3)°, V=1795.6(11) A~3 and Z=4. In this crystal structure, cyclooctanone prefers to reside in a chair-boat conformation. The structure is stabilized by attractive molecular force such as CH/π interaction called hydrophobic interaction.