SEM AND TEM EVALUATION OF MODE OF ACTION OF Cremaspora triflora ON Stenotrophomonas maltophilia

摘要

Stenotrophomonas maltophilia is increasingly recognised as an important nosocomial pathogen. Treatment challenges are due to intrinsic resistance to many antibiotics as well as concerns over toxicity of the drug of choice, co-trimoxazole. It is the only species of the genus Stenotrophomonas known to infect humans and has been isolated from poultry eggs, fish, raw cows' and ewes' milk. There is documented evidence showing the development of resistance to antimicrobial agents from an array of pathogens isolated from commercial eggs or their washings, triggering serious public health threats and adding pressure to the already overburdened antibiotic resistance crisis. Natural products, either as pure compounds or as standardized plant extracts, provide unlimited opportunities for new drug leads because of the unparalleled availability of chemical variety.