New N-(2-carboxybenzyl)chitosan hybrid biocomposites for scaffolds applications

摘要

CBCS was successfully synthesized and identified by UV and H~1NMR spectra. Composite materials were prepared by adding TiO_2 nanoparticles at different concentrations and Bioglass 45S5 during the modification reaction. Porous scaffolds were obtained using the lyophilization technique and they were characterized. They all showed interconnected pores and high mechanical properties. In addition, swelling, degradation and bioactivity studies of the composite scaffolds were performed. The developed composite scaffolds were bioactive and showed controlled swelling and degradation rate by the addition of inoganic fillers.