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MICROMECHANICAL ANALYSIS OF TISSUES - THE EFFECT OF CELL ADHESION TO EXTRA CELLUALR MATRIX

机译:组织的微机械分析 - 细胞粘附对细胞外基质的影响

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Modeling of interactions between cell and extra cellular matrix (ECM) is essential in a cell and tissue injury study. Several studies have been conducted to realize the role of mechanical property of a cell and ECM in a tissue exposed to an external loading. In this study we have used a micromechanical approach by assuming two representative volume elements (RVE) with different packing of cell inside the matrix to characterize the mechanical property of the composite formed by the cell and the ECM in a tissue. In the micromechanical modeling procedure, the cell-ECM adhesion will be studied in detail. The results will clarify the role of cell adhesion in load transferring characteristics inside the cell -^sECM composite.
机译:细胞和额外细胞基质(ECM)的相互作用建模对细胞和组织损伤研究至关重要。已经进行了几项研究以实现细胞和ECM在暴露于外部负荷的组织中的力学性能的作用。在该研究中,我们通过假设具有基质内的细胞的两个代表性体积(RVE)来使用微机械方法,以表征由细胞和组织中的细胞形成的复合物的机械性能。在微机械建模程序中,将详细研究细胞-ECM粘附。结果将阐明细胞粘附在电池 - ^ SECM复合材料中负荷转移特性的作用。

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