(cest2017_01272) Removal and transformation of citalopram and 4 of its biotransformation products during ozonation

摘要

The continuous discharge of pharmaceuticals in effluents from production facilities, hospitals, and private households,improper disposal of unused drugs, and the direct discharge of veterinary medicines all lead to contamination ofenvironmental waters [Kümmerer (2001)]. Many pharmaceuticals are not entirely removed even through wastewater ordrinking water treatment processes, thus, they are consequently detected at various concentrations (from ng to μg per liter)in effluent samples of wastewater treatment plants (WWTPs) and drinking water supplies [Kumar and Xagoraraki (2010)].Citalopram (CTR), a selective serotonin re-uptake inhibitor, is a compound of interest due to its worldwide highconsumption for the treatment of depression. Several studies carried out worldwide reported the occurrence of CTR indifferent environmental matrices, including influent and effluent wastewaters, sewage sludge, surface waters and biota[Beretsou (2016)].