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Structural modification of 2-aminoisobutylic acid containing peptides toward an acquiring of antimicrobial activities against pathogenic bacteria

机译:含2-氨基二丁基酸肽对致病性细菌的抗菌活性的结构改性

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Availability of Aib containing cationic peptides on antimicrobial action was evaluated. BRBA20; consists of five repeated Aib-Arg-Aib-Ala, showed strong antibacterial activity against Gram-positive and-negative bacteria, as well as several drug-resistant strains through membrane disruption.
机译:评估含有阳离子肽的AIB的可用性进行抗菌作用。 BRBA20;由五次重复的AIB-Arg-AIB-ALA组成,表现出对革兰氏阳性和阴性细菌的强烈抗菌活性,以及​​通过膜破坏的几种耐药菌株。

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