Different Surface Modification Techniques Have the Ability to Improve the Performance of Biodegradable Scaffolds Produced by Rapid Prototyping.

摘要

In bone-tissue engineering the use of biodegradable scaffolds based on biodegradable polyesters has demonstrated great potential. Of special interest are the 100% interconnective scaffolds which are created from poly-s-caprolactone (PCL) by rapid-prototyping. Major advantages include the flexibility in scaffold design and the control over the mechanical properties and pore sizes. An important drawback of PCL is the hydrophobic character of the surface. In order to improve cell-adhesion, cell-viability and cell-proliferation, different surface modification techniques can be proposed.