Effective Strategies for Streamlining SPE Processing using Novel 96-well Plate based Components prior to LC-MS/MS Analysis

摘要

Excellent recoveries and RSDs were observed using the load-wash-elute methodology and demonstrated minimal difference compared to standard processing. The results demonstrated that it is possible to perform SPE without conditioning and equilibration steps when using the optimized components and water wettable sorbent chemistries in EVOLUTE EXPRESS. As such faster work flow can be achieved for higher throughput and increased lab efficiency. Less clogging of aqueous samples was seen in these experiments. This is especially important when automation is involved.