Proteomic analysis identifies differentially expressed proteins after red propolis extract treatment in Hep-2 cells

摘要

The data here presented indicate that red propolis is composed of complex molecules and exhibits important biological properties with capacity to inhibit tumor cell growth in a selective manner. Although the molecular mechanisms by which propolis interacts with cell metabolism remains unclear, further studies including isolation of majority bioactive compounds with cytogenetic and molecular tests will better elucidate the antioxidant and anticancer activities here observed. Isolated compost should also be investigated regarding its biological properties against different tumor and non-tumor cell lines.