Automated intact mass analysis for routine identity testing and quality tracking of recombinant monoclonal antibodies

摘要

1. BPC provides fast, high throughput, standardized workflows, with easy access to processed data. 2. Using these BPC-enabled workflows throughput increased to close to 100 samples/day including data processing and evaluation compared to 20-30 samples with manual processing and evaluation. 3. The setup has enabled us to confirm identity of all purified antibodies instantly, as well as building substantial quality into our clone selection process as well as early and late process development.