Rapid Degradation of Fluoxetine using Fe~(III)-TAMLs/H_(2)O_(2) System Inspiring Green Pharmaceutical Design

机译：使用Fe〜（iii）-tamls / h_（2）o_（2）系统鼓舞绿色药物设计的快速降解氟西汀

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Fluxetine was rapidly degraded by Fe~(III)-TAMLs/H_(2)O_(2). Intermediate fluoxetine aldehyde susceptible to nucleophilic attack provokes the avalanche of degradation. The discovered degradation mechanism is intriguing and is potentially instructive in green pharmaceutical design.

机译：通过Fe〜（III）-Tamls / H_（2）O_（2）迅速降解浮曲线。中间氟苯甲酯醛易患亲核袭击，引起降解的雪崩。发现的降解机制是有趣的，在绿色药物设计中是潜在的有效性。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2011年||共1页
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Longzhu Q. Shen; Dwight J. Tshudy; Edward P. Zovinka; Mark E. Bier; Terrence J. Collins;
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机译：Fe〜（III）-TAML催化H2O2和有机过氧化物对偶氮染料Orange II的绿色氧化降解：产物，毒性，动力学和机理
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4. Rapid Degradation of Fluoxetine using Fe~(III)-TAMLs/H_(2)O_(2) System Inspiring Green Pharmaceutical Design [C] . Longzhu Q. Shen, Dwight J. Tshudy, Edward P. Zovinka, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

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Rapid Degradation of Fluoxetine using Fe~(III)-TAMLs/H_(2)O_(2) System Inspiring Green Pharmaceutical Design

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