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Determination of Tacrolimus in Rat Whole Blood Using Dried Blood Spot (DBS) Analyses by LC-MS/MS

机译:用干血斑(DBS)分析LC-MS / MS对大鼠全血的凝胶蛋白

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A robust and reliable method has been established for the measurement of Tacrolimus in rat whole blood, with K_(2)EDTA as anticoagulant, using dried blood spot analysis by LC-MS/MS. The method meets FDA guidelines for bioanalytical procedures and is suitable for pre-clinical analysis.
机译:已经建立了一种稳健且可靠的方法,用于测量大鼠全血中的标准杆菌,K_(2)EDTA作为抗凝血剂,使用LC-MS / MS使用干血斑分析。该方法符合生物分析程序的FDA指南,适用于临床前分析。

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